Multiple Myeloma – Unusual Signs and Management

Multiple myeloma is a rare cancer that attacks the plasma cells in the bone marrow. Myeloma occurs when one of the plasma cells starts malfunctioning or begins to divide uncontrollably. The initial symptoms of the disease can go unnoticed till cancer spreads to other parts of the body. Hence recognizing the uncommon signs will help identify the condition at an early stage. Read on to learn about the nutritional regime and lifestyle changes to follow.
 5 unusual symptoms of multiple myeloma 
  When the plasma cells become cancerous, they grow uncontrollably within the bone marrow, crowding out healthy blood cells like red blood cells and platelets. Some patients who receive treatment could show little to no change and reoccurring symptoms. When cancer does not respond to treatment or recurs, this condition is known as relapsed refractory multiple myeloma. One can also face other unusual symptoms like:  
 Rib pain 
  If the tumor is near or compressing the spinal cord, some may also feel a shooting pain that starts in the rib and passes through the leg.   
 Repeated fractures 
  Myeloma damages the bones, making them weak and thin. It also causes lytic bone lesions leading to the loss of pockets of bone. Hence, repeated fractures are a symptom of multiple myeloma.  
 Unusual and excessive bleeding 
  Multiple myeloma can interfere with platelet production, which is crucial for blood clotting. With reduced platelets, one can face frequent bruising and bleeds. Frequent nosebleeds, bleeding in the gums, and heavy menstrual bleeding could be signs of multiple myeloma.  
 Hyperviscosity 
  Myeloma cells produce abnormal proteins and abnormal immunoglobulin molecules, which cause the blood to thicken. This condition is called hyperviscosity. Because it is thick, blood may not be able to reach the brain tissues easily. It may interfere with the process of communication between brain cells. This can lead to confusion in some.  
 Severe constipation 
  The degeneration of bones causes the accumulation of calcium in the blood, and the kidney now has to work harder to flush out the excess calcium, which requires a lot of water. With less water in the body, one may find it hard to push out stools leading to constipation.  
 Foods that can improve multiple myeloma symptoms 
  A balanced meal plan with adequate fluid intake is crucial for multiple myeloma to fight fatigue, increase energy, and cope with the effects of treatment. The meal plan should be rich in proteins, minerals, and important nutrients to help manage the symptoms and prevent them from worsening. It should also be kidney-friendly, promote new cell growth, help bone health, and fight anemia. Food ideal for multiple myeloma are:  
 Protein-rich  food 
  Protein-rich food helps to replace old cells and the cells damaged by multiple myeloma. It also helps build one’s immune system. It is best to include lean protein in regular meals. Protein-rich food recommended for multiple myeloma include: 
  Fish 
  Chicken and turkey 
  Eggs 
  Yogurt 
  Beans 
  Nuts and nut butter 
  Soy-based foods 
  Tofu  
 Fruits, vegetables, and greens 
  Fruits, vegetables, and greens are superfoods for vitamins, minerals, and antioxidants. They can help improve symptoms like constipation, increase nutritional levels, prevent oxidative stress, and fight infections. Always cook the fruits and vegetables well before eating. Some fruits and vegetables that are best suited for multiple myeloma include: 
  Papaya 
  Pineapple 
  Guava 
  Pumpkin 
  Green pepper 
  Brussel sprouts 
  Spinach 
  Broccoli  
 Fiber-rich foods 
  Constipation is one of the symptoms of multiple myeloma. Fiber-rich food can help fight constipation and empty the bowels. Fiber-rich food includes: 
  Apples 
  Pears 
  Whole grains 
  Beans 
  Legumes 
  Lentils 
  Celery 
  Artichokes  
 Iron-rich food 
  The cancer cells that build in the bone marrow may overthrow the healthy blood cells. This may lead to anemia.  Iron-rich food can improve blood cells and fight anemia, fatigue, and weakness. Some iron-rich food sources include: 
  Clams 
  Liver 
  Lean meat 
  Sardines 
  Leafy green vegetables 
  Chickpeas 
  Dates 
  Green peas  
 Folate 
  Folate can help increase the production of red and white blood cells in the bone marrow. It can compensate for the loss of blood cells caused by myeloma cells. Folate-rich food can help improve red blood cell count and build immunity. Important food sources of folate include: 
  Asparagus 
  Beef liver 
  Black-eyed beans 
  Kidney beans 
  Chickpeas 
  Fortified cereals 
  Green leafy vegetables  
 Foods to avoid and limit for multiple myeloma 
  There is no specific nutritional regime that doctors prescribe for multiple myeloma. The best strategy for planning a meal plan is to include foods that can help manage the symptoms and limit or avoid foods that can worsen the symptoms. Some foods that one should avoid for multiple myeloma include:  
 S  ugary desserts 
  Though one does not have to give up sugar completely, avoiding sugar-laden foods is recommended as it has zero nutritional value and may contribute to worsening the symptoms. Avoid or limit foods and beverages like carbonated drinks, candy, donuts, and cakes with a lot of cream and frosting.  
 Raw or uncooked food 
  Frequent infections are a symptom of multiple myeloma. Uncooked or undercooked food can carry bacteria that can cause infections. Washing them well and cooking them reduces the risk of infection. Avoid the following raw food: 
  Raw or undercooked meat 
  Raw or undercooked eggs 
  Uncooked vegetables 
  Overcooked vegetables 
  Sushi 
  Raw or unpasteurized dairy products 
  Raw sprouts 
  Raw salad dressings  
 Processed foods 
  Processed foods have too many trans and unsaturated fats and contains many chemicals and preservatives that increase its shelf life. Avoid the following: 
  Non-dried deli meats 
  Highly processed foods 
  Packed and ready-to-eat food 
  Snacks  
 Potassium-rich food 
  Since multiple myeloma affects the kidneys, if one’s meal plan has too much potassium, they may not be able to work well enough to flush the excess potassium from the body. Avoid high-potassium foods like: 
  Avocado 
  Banana 
  Melons 
  Orange 
  Prunes 
  Raisins 
  Granola 
  Brown rice 
  Beans  
Food with little potassium poses no danger and can be eaten in moderation.
 Phosphorus-rich food 
  Avoid phosphorus-rich food, as the kidneys may be unable to flush it out. This causes the build-up of phosphorus in the blood, which can further weaken the bones. Avoid the following foods:   
  Bran cereals 
  Oatmeal 
  Dark-colored colas  





